El estudio científico del estrés crónico en neurociencias y psicooncología

  • Manolete S. Moscoso University of South Florida (Estados Unidos)
Palabras clave: Estrés crónico, Conciencia plena, Neurociencias, Alostasis, Psicología, Enfermos de cáncer

Resumen

Presentamos un análisis de las limitaciones metodológicas del estudio del estrés y del concepto de homeostasis. También, se describe un nuevo modelo acerca del estrés crónico, allostasis y carga allostática, que explica las interacciones entre el cerebro y los sistemas nervioso, endocrino e inmune en las causas de enfermedades físicas y mentales. Ilustramos empíricamente, con base en nuestras investigaciones, cómo este nuevo marco metodológico de investigación científica permite la integración multidisciplinaria de las ciencias biomédicas y las ciencias del comportamiento, reflejando el gran avance científico actual observado en el campo de las neurociencias y de la psicooncología. Se examina el impacto negativo del estrés crónico en la salud del individuo, poniendo énfasis en el rol central que cumple el concepto del distrés emocional percibido. Presentamos la terapia cognitiva centrada en mindfulness como una respuesta de tratamiento multidisciplinario en las áreas de la neurociencia y la psicooncología.

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Armeli, S., Todd, M., Mohr, C. (2005). A daily process approach to individual differences in stress-related alcohol use. Journal of Personality, 73, 6, 1-30.

Bishop, S. R. (2002). What do we really know about mindfulness-based stress reduction? Psychosomatic Medicine, 64, 71-83.

Cannon, W. B. (1915). Bodily Changes in Pain, Hunger, Fear and Rage. Boston, MA: C.T. Branford Co., Inc.

Cannon, W. B. (1932). The Wisdom of the Body. Nueva York: W.W. Norton and Co., Inc.

Carlson, L. E., Speca, M., Patel, K. D., Faris, P. (2007). One year pre-post intervention follow-up of psychological, immune, endocrine and blood pressure outcomes of mindfulnessbased stress reduction (MBSR) in breast and prostate cancer outpatients. Brain, Behavior and Immunology, 21, 1038-1049.

Cassileth, B. R., Lusk, E. J., Hutter, R., Strouse, T. B., & Brown, L. I. (1984). Concordance of depression and anxiety in patients with cancer. Psychological Reports, 54, 588-590.

Dallman, M. F. (2003). Chronic stress and obesity: A new view of “comfort food”. Proccedings of the National Academy of Science, 100, 11696-11701.

Dhabhar, F. S., McEwen, B. S. (1997). Acute stress enhances while chronic stress suppresses cell-mediated immunity in vivo: A potential role for leukocyte trafficking. Brain, Behavior and Immunity, 114, 286-306.

Epel, E., Lapidus, R., McEwen, B. (2000). Stress may add bite to appetite in women: A laboratory study of stress-induced cortisol and eating behavior. Psychoneuroendocrinology, 26, 37-49.

Flook, L., Goldberg, S. B., Pinger, L., Bonus, K., & Davidson, R. J. (2013). Mindfulness for teachers: A pilot study to assess effects on stress, burnout and teaching efficacy. Mind, Brain and Education, 7, 182-195. Doi: 10.1111/mbe.12026. PMCID: PMC3855679.

Garland, E. L., Gaylord, S. A., & Fredrickson, B. L. (2011). Positive appraisal mediates the stressreductive effects of mindfulness: An upward spiral process. Mindfulness, 2, 59-67.

Koob, G. F. (1999). Corticotropinreleasing factor, norepinephrine and stress. Biological Psychiatry, 46, 1167-1180.

Lane, R. D., & Wager T. D. (2009). The new field of brain-body medicine: What have we learned and where are we headed? NeuroImage, 47, 11351140.

Lazarus, R. S. (1993). Coping theory and research: Past, present and future. Psychosomatic Medicine, 55, 3, 234-247.

Lazarus, R. S., & Folkman, S. (1984). Stress, Appraisal and Coping. Nueva York: Springer.

Lengacher, C. A., Kip, K. E., Moscoso, M., Johnson-Mallard, V., Molinari, M., Gaurkee, D., & Greenberg, H. (2007). Mindfulness-Based Stress Reduction (MBSR) improves psychological status and general health among breast cancer survivors. Psycho-Oncology, 16, 3, S72-S73.

Lengacher, C. A., Kip, K., Barta, M., Jacobsen, P. B., Groer, M., Lehman, B., & Molinary, M. S. (2012). A pilot study evaluating the effects of Mindfulness Based Stress Reduction on psychological status, physical status, salivary cortisol, Interleukin-6 among advanced-stage cancer patients and their caregivers. Journal of Holistic Nursing, 30, 170-185.

Lengacher, C. A., Kip, K., Post-White, J., Fitzgerald, S., Newton, C., Barta., & Jacobson, P. B. (2013). Lymphocyte Recovery after Breast Cancer Treatment and Mindfulness-Based Stress Reduction (MBSR) Therapy. Journal of Biological Research for Nursing, 15, 1, 37-47.

Lengacher, C., Johnson-Mallard, V., PostWhite, J., Moscoso, M., Jacobsen, P., Klein, T., & Kip, K. (2009). Randomized controlled trial of mindfulnessbased stress reduction (MBSR) for survivors of breast cancer. PsychoOncology, 18, 12, 1261-1272. Doi: 10.1002/pon.1529: 10.1002/pon.1529.

Lengacher, C. A., Reich, R. R., Kip, K. E., Barta, M., Ramesar, S., Paterson, C. L., & Park, J. Y. (2014). Influence of Mindfulness-Based Stress Reduction on Telomerase Activity in Women with Breast Cancer (BC). Biological Reseach for Nursing. Doi: 10. 1177.

Lengacher, C., Reich, R., Post-White, J., Moscoso, M., Shelton, M., Barta, M., & Budhrani, P. (2012). Mindfulness based stress reduction in posttreatment breast cancer patients: An examination of symptoms and symptom clusters. Journal of Behavioral Medicine, 35, 86-94. Doi: 2011.10.1007/s10865-011-9346-4: 10.1007/s10865-011-9346-4.

Levine, S. (2001). Primary social relationships influence the development of the hypothalamic-pituitary-adrenal axis in the rat. Physiology & Behavior, 73, 255-260.

Lupien, S. J., McEwen, B. S., Gunnar, M. R., & Heim, C. (2009). Effects of the stress throughout the lifespan on the brain, behavior and cognition. Nature Reviews Neuroscience, 10, 6, 434-445.

MacPherson, A., Dinkel, K., & Sapolsky, R. (2005). Glucorticoids worsen ex citotoxin-induced expression of proinflammatory cytokines in hippocampal cultures. Experimental Neurology, 194, 376-383.

McEwen, B. S. (1998). Protective and Damaging Effects of Stress Mediators. New England Journal of Medicine, 338, 171-179.

McEwen, B. S. (2001). Plasticity of the hippocampus: adaptation to chronic stress and allostatic load. Annals of the New York Academy of Sciences, 933, 265-277.

McEwen, B. S. (2006). Sleep deprivation as a neurobiologic and physiologic stressor, allostastis and allostatic load. Metabolism, 55, S20-S23.

McEwen, B. S. (2007). The physiology and neurobiology of stress and adaptation: Central role of the brain. Physiological Reviews, 87, 873-904.

McEwen, B. S., & Stellar, E. (1993). Stress and the individual: Mechanisms leading to disease. Archives of Internal Medicine, 153, 2093-2101.

McEwen, B. S., & Wingfield, J. C. (2003). The concept of allostasis in biology and biomedicine. Hormones & Behavior, 43, 2-15.

Moscoso, M. S. (2009). De la mente a la célula: impacto del estrés en psiconeuroinmunoendocrinología. Revista Liberabit, 15, 2, 143-152.

Moscoso, M. S. (2010). El estrés crónico y la terapia cognitiva centrada en mindfulness: una nueva dimensión en psiconeuroinmunología. Revista Persona, 13, 11-29.

Moscoso, M. S. (2011). El estrés crónico y la medición psicométrica de distrés emocional percibido en medicina y psicología clínica de la salud. Revista Liberabit, 17, 1, 67-76.

Moscoso, M. S., Lengacher, C. A., & Reheiser, E. C. (2012). The assessment of the perceived emotional distress: The neglected side of cancer care. Journal of Psicooncologia, 9, 2-3, 277-288.

Moscoso, M. S., McCreary, D., Goldenfarb, P., Knapp, M., & Reheiser, E. (2000). A brief screening inventory to measure emotional distress in cancer patients. Psycho-Oncology, 9, 5, S53.

Moscoso, M. S., & Reheiser, E. C. (2010). Construct validity of the Emotional Distress Inventory in patients with cancer. Ansiedad y Estrés, 16, 1, 83-94.

Moscoso, M. S., Reheiser, E. C., & Hann, D. (2004). Effects of a brief mindfulness-based stress reduction intervention on cancer patients. Psycho-Oncology, 13, 1, S12.

Sapolsky, R. M. (1986). Glucocorticoid toxicity in the hippocampus reversal by supplementation with brain fuels. The Journal of Neuroscience, 6, 2240-2244.

Sapolsky, R. M. (1996). Why stress is bad for your brain. Science, 273, 749-750.

Sapolsky, R. M., Romero, L. M., & Munck, A. U. (2000). How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory and preparative actions. Endocrine Review, 21, 55-89.

Schulkin, J. (2003). Rethinking homeostasis: Allostatic regulation in physiology and pathophysiology. Cambridge, MA: MIT Press.

Segal, Z. V., Williams, M. G., & Teasdale, J. D. (2001). Mindfulness-Based Cognitive Therapy for Depression: A New Approach to Preventing Relapse. Columbus, OH: The Guilford Press.

Selye, H. (1936). A syndrome produced by diverse nocuous agents. Nature, 138, 32.

Speca, M., Carlson, L. E., Goodey, E., & Angen, M. (2000). A randomized, wait-list controlled clinical trial: The effect of a mindfulness meditationbased stress reduction program on mood and symptoms of stress in cancer outpatients. Psychosomatic Medicine, 62, 613-622.

Sterling, P., & Eyer, J. (1988). Allostasis, a new paradigm to explain arousal pathology. En S. Fisher, & J. Reason (Eds.), Handbook of life stress, cognition and health (pp. 629-649). Nueva York: John Wiley & Sons.

Publicado
2014-03-20
Cómo citar
Moscoso, M. S. (2014). El estudio científico del estrés crónico en neurociencias y psicooncología. Persona, (017), 53-70. https://doi.org/10.26439/persona2014.n017.288
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